Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation

Acute respiratory distress syndrome (ARDS) is characterized by an excessive acute inflammatory response in lung parenchyma, which ultimately leads to refractory hypoxemia. One of the earliest abnormalities seen in lung injury is the elevated levels of inflammatory cytokines, among them, the soluble...

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Detalles Bibliográficos
Autores principales: Pooladanda, Venkatesh, Thatikonda, Sowjanya, Bale, Swarna, Pattnaik, Bijay, Sigalapalli, Dilep Kumar, Bathini, Nagendra Babu, Singh, Shashi Bala, Godugu, Chandraiah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349848/
https://www.ncbi.nlm.nih.gov/pubmed/30692512
http://dx.doi.org/10.1038/s41419-018-1247-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349848/
https://www.ncbi.nlm.nih.gov/pubmed/30692512
http://dx.doi.org/10.1038/s41419-018-1247-9

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