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Cancer cell-derived immunoglobulin G activates platelets by binding to platelet FcγRIIa

Tumor-associated thrombosis is the second leading risk factor for cancer patient death, and platelets activity is abnormal in cancer patients. Discovering the mechanism of platelet activation and providing effective targets for therapy are urgently needed. Cancer cell- derived IgG has been reported...

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Detalles Bibliográficos
Autores principales: Miao, Shuo, Shu, Dan, Zhu, Ying, Lu, Meng, Zhang, Qingsong, Pei, Youliang, He, Ao-Di, Ma, Rong, Zhang, Bixiang, Ming, Zhang-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349849/
https://www.ncbi.nlm.nih.gov/pubmed/30692520
http://dx.doi.org/10.1038/s41419-019-1367-x