The palladacycle complex AJ-5 induces apoptotic cell death while reducing autophagic flux in rhabdomyosarcoma cells

Rhabdomyosarcoma (RMS) forms in skeletal muscle and is the most common soft tissue sarcoma in children and adolescents. Current treatment is associated with debilitating side effects and treatment outcomes for patients with metastatic disease are dismal. Recently, a novel binuclear palladacycle, AJ-...

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Detalles Bibliográficos
Autores principales: Bleloch, Jenna Susan, du Toit, André, Gibhard, Liezl, Kimani, Serah, Ballim, Reyna Deeya, Lee, Minkyu, Blanckenberg, Angelique, Mapolie, Selwyn, Wiesner, Lubbe, Loos, Ben, Prince, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349869/
https://www.ncbi.nlm.nih.gov/pubmed/30701092
http://dx.doi.org/10.1038/s41420-019-0139-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349869/
https://www.ncbi.nlm.nih.gov/pubmed/30701092
http://dx.doi.org/10.1038/s41420-019-0139-9

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