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The palladacycle complex AJ-5 induces apoptotic cell death while reducing autophagic flux in rhabdomyosarcoma cells
Rhabdomyosarcoma (RMS) forms in skeletal muscle and is the most common soft tissue sarcoma in children and adolescents. Current treatment is associated with debilitating side effects and treatment outcomes for patients with metastatic disease are dismal. Recently, a novel binuclear palladacycle, AJ-...
Autores principales: | Bleloch, Jenna Susan, du Toit, André, Gibhard, Liezl, Kimani, Serah, Ballim, Reyna Deeya, Lee, Minkyu, Blanckenberg, Angelique, Mapolie, Selwyn, Wiesner, Lubbe, Loos, Ben, Prince, Sharon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349869/ https://www.ncbi.nlm.nih.gov/pubmed/30701092 http://dx.doi.org/10.1038/s41420-019-0139-9 |
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