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TRAIL inhibits RANK signaling and suppresses osteoclast activation via inhibiting lipid raft assembly and TRAF6 recruitment

Human osteoclast formation from mononuclear phagocyte precursors involves interactions between members of the tumor necrosis factor (TNF) ligand superfamily and their receptors. Recent evidence indicated that TNF-α-related apoptosis-inducing ligand (TRAIL) induces osteoclast differentiation via a TR...

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Detalles Bibliográficos
Autores principales: Liao, Hsiu-Jung, Tsai, Hwei-Fang, Wu, Chien-Sheng, Chyuan, I.-Tsu, Hsu, Ping-Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349873/
https://www.ncbi.nlm.nih.gov/pubmed/30692521
http://dx.doi.org/10.1038/s41419-019-1353-3