Hypoxia-induced 26S proteasome dysfunction increases immunogenicity of mesenchymal stem cells

Bone marrow-derived allogeneic (donor derived) mesenchymal stem cells (MSCs) are immunoprivileged and are considered to be prominent candidates for regenerative therapy for numerous degenerative diseases. Even though the outcome of initial allogeneic MSCs based clinical trials was encouraging, the o...

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Detalles Bibliográficos
Autores principales: Abu-El-Rub, Ejlal, Sequiera, Glen Lester, Sareen, Niketa, Yan, Weiang, Moudgil, Meenal, Sabbir, Mohammad Golam, Dhingra, Sanjiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349874/
https://www.ncbi.nlm.nih.gov/pubmed/30692516
http://dx.doi.org/10.1038/s41419-019-1359-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349874/
https://www.ncbi.nlm.nih.gov/pubmed/30692516
http://dx.doi.org/10.1038/s41419-019-1359-x

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