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Hypoxia-induced 26S proteasome dysfunction increases immunogenicity of mesenchymal stem cells
Bone marrow-derived allogeneic (donor derived) mesenchymal stem cells (MSCs) are immunoprivileged and are considered to be prominent candidates for regenerative therapy for numerous degenerative diseases. Even though the outcome of initial allogeneic MSCs based clinical trials was encouraging, the o...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349874/ https://www.ncbi.nlm.nih.gov/pubmed/30692516 http://dx.doi.org/10.1038/s41419-019-1359-x |