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TRPC5 ion channel permeation promotes weight gain in hypercholesterolaemic mice
Transient Receptor Potential Canonical 5 (TRPC5) is a subunit of a Ca(2+)-permeable non-selective cationic channel which negatively regulates adiponectin but not leptin in mice fed chow diet. Adiponectin is a major anti-inflammatory mediator and so we hypothesized an effect of TRPC5 on the inflammat...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349875/ https://www.ncbi.nlm.nih.gov/pubmed/30692584 http://dx.doi.org/10.1038/s41598-018-37299-8 |