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TRPC5 ion channel permeation promotes weight gain in hypercholesterolaemic mice

Transient Receptor Potential Canonical 5 (TRPC5) is a subunit of a Ca(2+)-permeable non-selective cationic channel which negatively regulates adiponectin but not leptin in mice fed chow diet. Adiponectin is a major anti-inflammatory mediator and so we hypothesized an effect of TRPC5 on the inflammat...

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Detalles Bibliográficos
Autores principales:	Rode, Baptiste, Yuldasheva, Nadira Y., Baxter, Paul D., Sedo, Alicia, Ainscough, Justin F., Shires, Michael, Kearney, Mark T., Bailey, Marc A., Wheatcroft, Stephen B., Beech, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349875/ https://www.ncbi.nlm.nih.gov/pubmed/30692584 http://dx.doi.org/10.1038/s41598-018-37299-8

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