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Autophagy attenuates tubulointerstital fibrosis through regulating transforming growth factor-β and NLRP3 inflammasome signaling pathway

Renal fibrosis is the final common pathway of various renal injuries and it leads to chronic kidney disease. Autophagy is a cellular process of degradation of damaged cytoplasmic components and regulates cell death and proliferation. Cellular response during unilateral ureteral obstruction (UUO) is...

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Detalles Bibliográficos
Autores principales: Nam, Sun Ah, Kim, Wan-Young, Kim, Jin Won, Park, Sang Hee, Kim, Hong Lim, Lee, Myung-Shik, Komatsu, Masaaki, Ha, Hunjoo, Lim, Ji Hee, Park, Cheol Whee, Yang, Chul Woo, Kim, Jin, Kim, Yong Kyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349890/
https://www.ncbi.nlm.nih.gov/pubmed/30692509
http://dx.doi.org/10.1038/s41419-019-1356-0