Selective inhibition of mitochondrial sodium-calcium exchanger protects striatal neurons from α-synuclein plus rotenone induced toxicity

Progressive accumulation of α-synuclein (α-syn) and exposure to environmental toxins are risk factors that may both concur to Parkinson’s disease (PD) pathogenesis. Electrophysiological recordings of field postsynaptic potentials (fEPSPs) and Ca(2+) measures in striatal brain slices and differentiat...

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Detalles Bibliográficos
Autores principales: Bastioli, Guendalina, Piccirillo, Silvia, Castaldo, Pasqualina, Magi, Simona, Tozzi, Alessandro, Amoroso, Salvatore, Calabresi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349907/
https://www.ncbi.nlm.nih.gov/pubmed/30692508
http://dx.doi.org/10.1038/s41419-018-1290-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349907/
https://www.ncbi.nlm.nih.gov/pubmed/30692508
http://dx.doi.org/10.1038/s41419-018-1290-6

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