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Cycles of protein condensation and discharge in nuclear organelles studied by fluorescence lifetime imaging

Nuclear organelles are viscous droplets, created by concentration-dependent condensation and liquid–liquid phase separation of soluble proteins. Nuclear organelles have been actively investigated for their role in cellular regulation and disease. However, these studies are highly challenging to perf...

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Detalles Bibliográficos
Autores principales: Pliss, Artem, Levchenko, Svitlana M., Liu, Lixin, Peng, Xiao, Ohulchanskyy, Tymish Y., Roy, Indrajit, Kuzmin, Andrey N., Qu, Junle, Prasad, Paras N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349932/
https://www.ncbi.nlm.nih.gov/pubmed/30692529
http://dx.doi.org/10.1038/s41467-019-08354-3