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Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation

Intestinal exocrine secretory cells, including Paneth and goblet cells, have a pivotal role in intestinal barrier function and mucosal immunity. Dysfunction of these cells may lead to the pathogenesis of human diseases such as inflammatory bowel disease (IBD). Therefore, identification and elucidati...

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Detalles Bibliográficos
Autores principales: Cai, Yafei, Zhu, Guangxun, Liu, Siyang, Pan, Zezheng, Quintero, Michaela, Poole, Candace J., Lu, Chunwan, Zhu, Huabin, Islam, Bianca, Riggelen, Jan van, Browning, Darren, Liu, Kebin, Blumberg, Richard, Singh, Nagendra, Li, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349939/
https://www.ncbi.nlm.nih.gov/pubmed/30701081
http://dx.doi.org/10.1038/s41421-018-0070-x