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Indispensable role of the Ubiquitin-fold modifier 1-specific E3 ligase in maintaining intestinal homeostasis and controlling gut inflammation
Intestinal exocrine secretory cells, including Paneth and goblet cells, have a pivotal role in intestinal barrier function and mucosal immunity. Dysfunction of these cells may lead to the pathogenesis of human diseases such as inflammatory bowel disease (IBD). Therefore, identification and elucidati...
Autores principales: | Cai, Yafei, Zhu, Guangxun, Liu, Siyang, Pan, Zezheng, Quintero, Michaela, Poole, Candace J., Lu, Chunwan, Zhu, Huabin, Islam, Bianca, Riggelen, Jan van, Browning, Darren, Liu, Kebin, Blumberg, Richard, Singh, Nagendra, Li, Honglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349939/ https://www.ncbi.nlm.nih.gov/pubmed/30701081 http://dx.doi.org/10.1038/s41421-018-0070-x |
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