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Intestinal epithelial N-acylphosphatidylethanolamine phospholipase D links dietary fat to metabolic adaptations in obesity and steatosis

Variations in N-acylethanolamines (NAE) levels are associated with obesity and metabolic comorbidities. Their role in the gut remains unclear. Therefore, we generated a mouse model of inducible intestinal epithelial cell (IEC)-specific deletion of N-acylphosphatidylethanolamine phospholipase D (NAPE...

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Detalles Bibliográficos
Autores principales: Everard, Amandine, Plovier, Hubert, Rastelli, Marialetizia, Van Hul, Matthias, de Wouters d’Oplinter, Alice, Geurts, Lucie, Druart, Céline, Robine, Sylvie, Delzenne, Nathalie M., Muccioli, Giulio G., de Vos, Willem M., Luquet, Serge, Flamand, Nicolas, Di Marzo, Vincenzo, Cani, Patrice D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349942/
https://www.ncbi.nlm.nih.gov/pubmed/30692526
http://dx.doi.org/10.1038/s41467-018-08051-7