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TREM2 acts as a tumor suppressor in hepatocellular carcinoma by targeting the PI3K/Akt/β-catenin pathway

Triggering receptor expressed on myeloid cells 2 (TREM2) is involved in nonmalignant pathological processes. However, TREM2’s function in malignant diseases, especially in hepatocellular carcinoma (HCC) remains unknown. In the present study, we report that TREM2 is a novel tumor suppressor in HCC. T...

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Detalles Bibliográficos
Autores principales: Tang, Wenqing, Lv, Bei, Yang, Biwei, Chen, Yukai, Yuan, Feifei, Ma, Lijie, Chen, She, Zhang, Si, Xia, Jinglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350080/
https://www.ncbi.nlm.nih.gov/pubmed/30683932
http://dx.doi.org/10.1038/s41389-018-0115-x