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Interplay between post-translational cyclooxygenase-2 modifications and the metabolic and proteomic profile in a colorectal cancer cohort

BACKGROUND: Colorectal cancer (CRC) is the second most common cause of cancer death worldwide. It is broadly described that cyclooxygenase-2 (COX-2) is mainly overexpressed in CRC but less is known regarding post-translational modifications of this enzyme that may regulate its activity, intracellula...

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Detalles Bibliográficos
Autores principales: Prieto, Patricia, Jaén, Rafael I, Calle, Daniel, Gómez-Serrano, María, Núñez, Estefanía, Fernández-Velasco, María, Martín-Sanz, Paloma, Alonso, Sergio, Vázquez, Jesús, Cerdán, Sebastián, Peinado, Miguel Ángel, Boscá, Lisardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350170/
https://www.ncbi.nlm.nih.gov/pubmed/30700940
http://dx.doi.org/10.3748/wjg.v25.i4.433