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A potential novel therapy for FGFR1-amplified pancreatic cancer with bone metastasis, screened by next-generation sequencing and a patient-derived xenograft model

Effective therapies are limited for pancreatic cancer, particularly for those with distant tumour metastases. Therefore, more individualised drug screening is urgently required. Next-generation sequencing (NGS) is a powerful tool to investigate the genomic landscape of patients and the mechanism of...

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Detalles Bibliográficos
Autores principales: Guan, Zhonghai, Lan, Huanrong, Sun, Dan, Wang, Xuanwei, Jin, Ketao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350188/
https://www.ncbi.nlm.nih.gov/pubmed/30719110
http://dx.doi.org/10.3892/ol.2018.9876