Cargando…

Overexpression of SIRT4 inhibits the proliferation of gastric cancer cells through cell cycle arrest

The sirtuins (SIRTs) are a family of nicotinamide-adenine dinucleotide (NAD)(+)-dependent protein deacetylases. SIRT4 is a mitochondrial NAD(+)-dependent adenosine diphsophate-ribosyltransferase. Recent studies demonstrated that SIRT4 can regulate glutamine metabolism and thus act as a tumor suppres...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Yiwang, Lin, Jiahao, Lin, Yao, Chen, Xuxu, Zhu, Guanbao, Huang, Guoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350193/
https://www.ncbi.nlm.nih.gov/pubmed/30745932
http://dx.doi.org/10.3892/ol.2018.9877