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Suppression of HMGB1 Released in the Glioblastoma Tumor Microenvironment Reduces Tumoral Edema

HMGB1 is a ubiquitously expressed intracellular protein that binds DNA and transcription factors and regulates chromosomal structure and function. Under conditions of cell death or stress, it is actively or passively released by cells into the extracellular environment, where it functions as damage-...

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Detalles Bibliográficos
Autores principales: Hong, Bangxing, Muili, Kamaldeen, Bolyard, Chelsea, Russell, Luke, Lee, Tae Jin, Banasavadi-Siddegowda, Yeshavanth, Yoo, Ji Young, Yan, Yuanqing, Ballester, Leomar Y., Bockhorst, Kurt H., Kaur, Balveen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350213/
https://www.ncbi.nlm.nih.gov/pubmed/30719499
http://dx.doi.org/10.1016/j.omto.2018.11.005