Microwave assisted synthesis of coumarin-purine derivatives: An approach to in vitro anti-oxidant, DNA cleavage, crystal structure, DFT studies and Hirshfeld surface analysis

An easy and efficient microwave-assisted protocol has been developed for the synthesis of coumarin-purine hybrids (3a-3j). The newly constructed 1,3-dimethyl-7-((substituted)-2-oxo-2H-chromen-4-yl)methyl)-1H-purine-2,6(3H,7H)-dione derivatives were evaluated for their in vitro antioxidant activity b...

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Detalles Bibliográficos
Autores principales: Mangasuli, Sumitra N., Hosamani, Kallappa M., Managutti, Praveen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350215/
https://www.ncbi.nlm.nih.gov/pubmed/30723822
http://dx.doi.org/10.1016/j.heliyon.2019.e01131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350215/
https://www.ncbi.nlm.nih.gov/pubmed/30723822
http://dx.doi.org/10.1016/j.heliyon.2019.e01131

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