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Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer

Oncolytic virotherapy is a promising approach for treating recurrent and/or drug-resistant ovarian cancer. However, its successful application in the clinic has been hampered by rapid immune-mediated clearance or neutralization of the virus, which reduces viral access to tumor foci. To overcome this...

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Detalles Bibliográficos
Autores principales: Mooney, Rachael, Majid, Asma Abdul, Batalla-Covello, Jennifer, Machado, Diana, Liu, Xueli, Gonzaga, Joanna, Tirughana, Revathiswari, Hammad, Mohamed, Lesniak, Maciej S., Curiel, David T., Aboody, Karen S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350263/
https://www.ncbi.nlm.nih.gov/pubmed/30719498
http://dx.doi.org/10.1016/j.omto.2018.12.003