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Clinicopathological and prognostic values of fibronectin and integrin αvβ3 expression in primary osteosarcoma

BACKGROUND: Osteosarcoma is a malignant bone tumor with a high potential for lung metastasis, and the prognosis for patients with metastatic disease is very poor. The interaction between fibronectin (FN) and integrin αvβ3 in soft-tissue sarcoma promotes cell migration, invasion, and lung metastasis....

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Detalles Bibliográficos
Autores principales: Shi, Kai, Wang, Sheng-lin, Shen, Bin, Yu, Feng-qiang, Weng, Dan-feng, Lin, Jian-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350278/
https://www.ncbi.nlm.nih.gov/pubmed/30691475
http://dx.doi.org/10.1186/s12957-019-1566-z