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Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer’s disease

Mitochondrial dysfunction is a key feature in both aging and neurodegenerative diseases including Alzheimer’s disease (AD), but the molecular signature that distinguishes pathological changes in the AD from healthy aging in the brain mitochondria remain poorly understood. In order to unveil AD speci...

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Detalles Bibliográficos
Autores principales: Adav, Sunil S, Park, Jung Eun, Sze, Siu Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350377/
https://www.ncbi.nlm.nih.gov/pubmed/30691479
http://dx.doi.org/10.1186/s13041-019-0430-y