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Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimer’s disease
Mitochondrial dysfunction is a key feature in both aging and neurodegenerative diseases including Alzheimer’s disease (AD), but the molecular signature that distinguishes pathological changes in the AD from healthy aging in the brain mitochondria remain poorly understood. In order to unveil AD speci...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350377/ https://www.ncbi.nlm.nih.gov/pubmed/30691479 http://dx.doi.org/10.1186/s13041-019-0430-y |