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Assessment of weighted topological overlap (wTO) to improve fidelity of gene co-expression networks

BACKGROUND: For more than a decade, gene expression data sets have been used as basis for the construction of co-expression networks used in systems biology investigations, leading to many important discoveries in a wide range of subjects spanning human disease to evolution and the development of or...

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Detalles Bibliográficos
Autores principales: Voigt, André, Almaas, Eivind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350380/
https://www.ncbi.nlm.nih.gov/pubmed/30691386
http://dx.doi.org/10.1186/s12859-019-2596-9