AAV2/8 Anti-angiogenic Gene Therapy Using Single-Chain Antibodies Inhibits Murine Choroidal Neovascularization

While anti-angiogenic therapies for wet age-related macular degeneration (AMD) are effective for many patients, they require multiple injections and are expensive and prone to complications. Gene therapy could be an elegant solution for this problem by providing a long-term source of anti-angiogenic...

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Detalles Bibliográficos
Autores principales: Hughes, Chris P., O’Flynn, Neil M.J., Gatherer, Maureen, McClements, Michelle E., Scott, Jennifer A., MacLaren, Robert E., Goverdhan, Srinivas, Glennie, Martin J., Lotery, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350388/
https://www.ncbi.nlm.nih.gov/pubmed/30719487
http://dx.doi.org/10.1016/j.omtm.2018.11.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350388/
https://www.ncbi.nlm.nih.gov/pubmed/30719487
http://dx.doi.org/10.1016/j.omtm.2018.11.005

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