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AAV2/8 Anti-angiogenic Gene Therapy Using Single-Chain Antibodies Inhibits Murine Choroidal Neovascularization
While anti-angiogenic therapies for wet age-related macular degeneration (AMD) are effective for many patients, they require multiple injections and are expensive and prone to complications. Gene therapy could be an elegant solution for this problem by providing a long-term source of anti-angiogenic...
Autores principales: | Hughes, Chris P., O’Flynn, Neil M.J., Gatherer, Maureen, McClements, Michelle E., Scott, Jennifer A., MacLaren, Robert E., Goverdhan, Srinivas, Glennie, Martin J., Lotery, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350388/ https://www.ncbi.nlm.nih.gov/pubmed/30719487 http://dx.doi.org/10.1016/j.omtm.2018.11.005 |
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