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Activation of dynamin-related protein 1 - dependent mitochondria fragmentation and suppression of osteosarcoma by cryptotanshinone

BACKGROUND: Discovering how to regulate mitochondrial function to reduce cancer growth holds great potential for future cancer therapy development. Here we explore the effects of cryptotanshinone (CPT), a natural product derived from Salvia miltiorrhiza, on mitochondria of osteosarcoma (OS) both in...

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Detalles Bibliográficos
Autores principales: Yen, Jia-Hau, Huang, Hung Sen, Chuang, Chia Ju, Huang, Sheng-Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350405/
https://www.ncbi.nlm.nih.gov/pubmed/30691497
http://dx.doi.org/10.1186/s13046-018-1008-8