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A Novel Human Pluripotent Stem Cell-Derived Neural Crest Model of Treacher Collins Syndrome Shows Defects in Cell Death and Migration

The neural crest (NC) is a transient multipotent cell population present during embryonic development. The NC can give rise to multiple cell types and is involved in a number of different diseases. Therefore, the development of new strategies to model NC in vitro enables investigations into the mech...

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Detalles Bibliográficos
Autores principales: Serrano, Felipe, Bernard, William George, Granata, Alessandra, Iyer, Dharini, Steventon, Ben, Kim, Matthew, Vallier, Ludovic, Gambardella, Laure, Sinha, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350417/
https://www.ncbi.nlm.nih.gov/pubmed/30375284
http://dx.doi.org/10.1089/scd.2017.0234