Cargando…

The discovery and enhanced properties of trichain lipids in lipopolyplex gene delivery systems

The formation of a novel trichain (TC) lipid was discovered when a cationic lipid possessing a terminal hydroxyl group and the helper lipid dioleoyl l-α-phosphatidylethanolamine (DOPE) were formulated as vesicles and stored. Importantly, the transfection efficacies of lipopolyplexes comprised of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Mohammadi, Atefeh, Kudsiova, Laila, Mustapa, M. Firouz Mohd, Campbell, Frederick, Vlaho, Danielle, Welser, Katharina, Story, Harriet, Tagalakis, Aristides D., Hart, Stephen L., Barlow, David J., Tabor, Alethea B., Lawrence, M. Jayne, Hailes, Helen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350505/
https://www.ncbi.nlm.nih.gov/pubmed/30629080
http://dx.doi.org/10.1039/c8ob02374c