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The discovery and enhanced properties of trichain lipids in lipopolyplex gene delivery systems
The formation of a novel trichain (TC) lipid was discovered when a cationic lipid possessing a terminal hydroxyl group and the helper lipid dioleoyl l-α-phosphatidylethanolamine (DOPE) were formulated as vesicles and stored. Importantly, the transfection efficacies of lipopolyplexes comprised of the...
Autores principales: | Mohammadi, Atefeh, Kudsiova, Laila, Mustapa, M. Firouz Mohd, Campbell, Frederick, Vlaho, Danielle, Welser, Katharina, Story, Harriet, Tagalakis, Aristides D., Hart, Stephen L., Barlow, David J., Tabor, Alethea B., Lawrence, M. Jayne, Hailes, Helen C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350505/ https://www.ncbi.nlm.nih.gov/pubmed/30629080 http://dx.doi.org/10.1039/c8ob02374c |
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