Metformin Counteracts HCC Progression and Metastasis Enhancing KLF6/p21 Expression and Downregulating the IGF Axis

BACKGROUND AND AIMS: Hepatocellular carcinoma (HCC) is the common tumor of the liver. Unfortunately, most HCC seem to be resistant to conventional chemotherapy and radiotherapy. The poor efficacy of antitumor agents is also due, at least in part, to the inefficient drug delivery and metabolism exert...

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Detalles Bibliográficos
Autores principales: Vacante, Fernanda, Senesi, Pamela, Montesano, Anna, Paini, Stefano, Luzi, Livio, Terruzzi, Ileana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350585/
https://www.ncbi.nlm.nih.gov/pubmed/30774659
http://dx.doi.org/10.1155/2019/7570146

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350585/
https://www.ncbi.nlm.nih.gov/pubmed/30774659
http://dx.doi.org/10.1155/2019/7570146

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