PDE5A Suppresses Proteasome Activity Leading to Insulin Resistance in C2C12 Myotubes

OBJECTIVE: The involvement of phosphodiesterase type 5 (PDE5) in the development of insulin resistance has been reported recently. However, the underlying molecular mechanism remains unclear. The present study aims at investigating the potential impacts of PDE5A on insulin signaling in C2C12 skeleta...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Tian, Xiaojun, Wu, Ti, Liu, Le, Guo, Yanghongyun, Wang, Changhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350610/
https://www.ncbi.nlm.nih.gov/pubmed/30774657
http://dx.doi.org/10.1155/2019/3054820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350610/
https://www.ncbi.nlm.nih.gov/pubmed/30774657
http://dx.doi.org/10.1155/2019/3054820

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