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mTOR-Dependent Oxidative Stress Regulates oxLDL-Induced Trained Innate Immunity in Human Monocytes

Introduction: Cells of the innate immune system particularly monocytes and macrophages have been recognized as pivotal players both during the initial insult as well as the chronic phase of atherosclerosis. It has recently been shown that oxidized low-density lipoprotein (oxLDL) induces a long-term...

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Detalles Bibliográficos
Autores principales: Sohrabi, Yahya, Lagache, Sina M. M., Schnack, Lucia, Godfrey, Rinesh, Kahles, Florian, Bruemmer, Dennis, Waltenberger, Johannes, Findeisen, Hannes M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350618/
https://www.ncbi.nlm.nih.gov/pubmed/30723479
http://dx.doi.org/10.3389/fimmu.2018.03155