Myelin basic protein charge isomers change macrophage polarization

PURPOSE: During a neuronal injury, a variety of immune cells infiltrate into the local microenvironment at the demyelination site. After the destruction of the intact myelin sheath, its major constituent myelin basic protein (MBP) dissociates from the plasma membrane and acts as a free ligand on the...

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Detalles Bibliográficos
Autores principales: Tsitsilashvili, Elene, Sepashvili, Maia, Chikviladze, Marika, Shanshiashvili, Lali, Mikeladze, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350649/
https://www.ncbi.nlm.nih.gov/pubmed/30774410
http://dx.doi.org/10.2147/JIR.S189570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350649/
https://www.ncbi.nlm.nih.gov/pubmed/30774410
http://dx.doi.org/10.2147/JIR.S189570

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