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Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity

Eradication of tumors by the immune system relies on the efficient activation of a T-cell response. For many years, the main focus of cancer immunotherapy has been on cytotoxic CD8 T-cell. However, stimulation of CD4 helper T cells is critical for the promotion and maintenance of immune memory, thus...

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Detalles Bibliográficos
Autores principales: Mensali, Nadia, Grenov, Amalie, Pati, Niladri Bhusan, Dillard, Pierre, Myhre, Marit Renée, Gaudernack, Gustav, Kvalheim, Gunnar, Inderberg, Else Marit, Bakke, Oddmund, Wälchli, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350688/
https://www.ncbi.nlm.nih.gov/pubmed/30723591
http://dx.doi.org/10.1080/2162402X.2018.1558663