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Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity
Eradication of tumors by the immune system relies on the efficient activation of a T-cell response. For many years, the main focus of cancer immunotherapy has been on cytotoxic CD8 T-cell. However, stimulation of CD4 helper T cells is critical for the promotion and maintenance of immune memory, thus...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350688/ https://www.ncbi.nlm.nih.gov/pubmed/30723591 http://dx.doi.org/10.1080/2162402X.2018.1558663 |