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Development of a peptide-based fluorescent probe for biological heme monitoring
Heme plays a vital role in cell biology and dysregulation of heme levels is implicated in a wide range of diseases. However, monitoring heme levels in biological systems is currently not straightforward. A short synthetic peptide probe containing 7-azatryptophan is shown to bind hemin in vitro with...
Autores principales: | Newton, Laura D., Pascu, Sofia I., Tyrrell, Rex M., Eggleston, Ian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Royal Society of Chemistry
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350759/ https://www.ncbi.nlm.nih.gov/pubmed/30574967 http://dx.doi.org/10.1039/c8ob02290a |
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