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Cilostazol protects hepatocytes against alcohol-induced apoptosis via activation of AMPK pathway

Alcoholic liver disease (ALD) is a worldwide health problem and hepatocyte apoptosis has been associated with the development/progression of ALD. However, no definite effective pharmacotherapy for ALD is currently available. Cilostazol, a selective type III phosphodiesterase inhibitor has been shown...

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Detalles Bibliográficos
Autores principales: Lee, Youn Ju, Shu, Mi-Sun, Kim, Jong-Yeon, Kim, Yun-Hye, Sim, Kyeong Hwa, Sung, Woo Jung, Eun, Jong Ryeol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350983/
https://www.ncbi.nlm.nih.gov/pubmed/30695051
http://dx.doi.org/10.1371/journal.pone.0211415