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Potentiation of P2RX7 as a host-directed strategy for control of mycobacterial infection

Mycobacterium tuberculosis is the leading worldwide cause of death due to a single infectious agent. Existing anti-tuberculous therapies require long treatments and are complicated by multi-drug-resistant strains. Host-directed therapies have been proposed as an orthogonal approach, but few have mov...

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Detalles Bibliográficos
Autores principales: Matty, Molly A, Knudsen, Daphne R, Walton, Eric M, Beerman, Rebecca W, Cronan, Mark R, Pyle, Charlie J, Hernandez, Rafael E, Tobin, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351102/
https://www.ncbi.nlm.nih.gov/pubmed/30693866
http://dx.doi.org/10.7554/eLife.39123