The ULK1-FBXW5-SEC23B nexus controls autophagy

In response to nutrient deprivation, the cell mobilizes an extensive amount of membrane to form and grow the autophagosome, allowing the progression of autophagy. By providing membranes and stimulating LC3 lipidation, COPII (Coat Protein Complex II) promotes autophagosome biogenesis. Here, we show t...

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Detalles Bibliográficos
Autores principales: Jeong, Yeon-Tae, Simoneschi, Daniele, Keegan, Sarah, Melville, David, Adler, Natalia S, Saraf, Anita, Florens, Laurence, Washburn, Michael P, Cavasotto, Claudio N, Fenyö, David, Cuervo, Ana Maria, Rossi, Mario, Pagano, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351106/
https://www.ncbi.nlm.nih.gov/pubmed/30596474
http://dx.doi.org/10.7554/eLife.42253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351106/
https://www.ncbi.nlm.nih.gov/pubmed/30596474
http://dx.doi.org/10.7554/eLife.42253

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