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Hepatocyte‐Specific β‐Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes

Liver regeneration after injury is normally mediated by proliferation of hepatocytes, although recent studies have suggested biliary epithelial cells (BECs) can differentiate into hepatocytes during severe liver injury when hepatocyte proliferation is impaired. We investigated the effect of hepatocy...

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Detalles Bibliográficos
Autores principales: Russell, Jacquelyn O., Lu, Wei‐Yu, Okabe, Hirohisa, Abrams, Marc, Oertel, Michael, Poddar, Minakshi, Singh, Sucha, Forbes, Stuart J., Monga, Satdarshan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351199/
https://www.ncbi.nlm.nih.gov/pubmed/30215850
http://dx.doi.org/10.1002/hep.30270