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Rosiglitazone reverses high fat diet-induced changes in BMAL1 function in muscle, fat, and liver tissue in mice

OBJECTIVE: Nutrient challenge in the form of a high fat (HF) diet causes a reversible reprogramming of the hepatic circadian clock. This depends in part on changes in the recruitment of the circadian transcription factor BMAL1 to genome targets, though the causes and extent of disruption to hepatic...

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Detalles Bibliográficos
Autores principales: Ribas-Latre, Aleix, Fekry, Baharan, Kwok, Christopher, Baumgartner, Corrine, Shivshankar, Samay, Sun, Kai, Chen, Zheng, Eckel-Mahan, Kristin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351224/
https://www.ncbi.nlm.nih.gov/pubmed/29795456
http://dx.doi.org/10.1038/s41366-018-0090-5