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Mitofusin1 in oocyte is essential for female fertility
Mitofusins (Mfn) are the important regulators of mitochondrial organization in mammalian cells; however, their roles during oocyte development remain unknown. In the present study, we generated mice with oocyte-specific knockout of Mfn1 or Mfn2 (Mfn1(fl/fl);Zp3-Cre or Mfn2(fl/fl);Zp3-Cre). We report...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351231/ https://www.ncbi.nlm.nih.gov/pubmed/30690319 http://dx.doi.org/10.1016/j.redox.2019.101110 |