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Computational Modeling of the Crosstalk Between Macrophage Polarization and Tumor Cell Plasticity in the Tumor Microenvironment

Tumor microenvironments contain multiple cell types interacting among one another via different signaling pathways. Furthermore, both cancer cells and different immune cells can display phenotypic plasticity in response to these communicating signals, thereby leading to complex spatiotemporal patter...

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Detalles Bibliográficos
Autores principales: Li, Xuefei, Jolly, Mohit Kumar, George, Jason T., Pienta, Kenneth J., Levine, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351454/
https://www.ncbi.nlm.nih.gov/pubmed/30729096
http://dx.doi.org/10.3389/fonc.2019.00010