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A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis

This study demonstrates that FGF10/FGFR2b signaling on distal epithelial progenitor cells, via ß-catenin/EP300, controls, through a comprehensive set of developmental genes, morphogenesis, and differentiation. Fibroblast growth factor (FGF) 10 signaling through FGF receptor 2b (FGFR2b) is mandatory...

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Detalles Bibliográficos
Autores principales: Jones, Matthew R., Dilai, Salma, Lingampally, Arun, Chao, Cho-Ming, Danopoulos, Soula, Carraro, Gianni, Mukhametshina, Regina, Wilhelm, Jochen, Baumgart-Vogt, Eveline, Al Alam, Denise, Chen, Chengshui, Minoo, Parviz, Zhang, Jin San, Bellusci, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351499/
https://www.ncbi.nlm.nih.gov/pubmed/30728831
http://dx.doi.org/10.3389/fgene.2018.00746