New insights into the coordination between the polymerization and 3′-5′ exonuclease activities in ϕ29 DNA polymerase

Bacteriophage ϕ29 DNA polymerase has two activities: DNA polymerization and 3′-5′ exonucleolysis governed by catalytic sites present in two structurally distant domains. These domains must work together to allow the correct replication of the template and to prevent the accumulation of errors in the...

Descripción completa

Detalles Bibliográficos
Autores principales: del Prado, Alicia, Rodríguez, Irene, Lázaro, José María, Moreno-Morcillo, María, de Vega, Miguel, Salas, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351526/
https://www.ncbi.nlm.nih.gov/pubmed/30696917
http://dx.doi.org/10.1038/s41598-018-37513-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351526/
https://www.ncbi.nlm.nih.gov/pubmed/30696917
http://dx.doi.org/10.1038/s41598-018-37513-7

Ejemplares similares