Acute glucose fluctuation impacts microglial activity, leading to inflammatory activation or self-degradation

Diabetes mellitus is associated with an increased risk of Alzheimer’s dementia and cognitive decline. The cause of neurodegeneration in chronic diabetic patients remains unclear. Changes in brain microglial activity due to glycemic fluctuations may be an etiological factor. Here, we examined the imp...

Descripción completa

Detalles Bibliográficos
Autores principales: Hsieh, Cheng-Fang, Liu, Ching-Kuan, Lee, Ching-Tien, Yu, Liang-En, Wang, Jiz-Yuh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351546/
https://www.ncbi.nlm.nih.gov/pubmed/30696869
http://dx.doi.org/10.1038/s41598-018-37215-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351546/
https://www.ncbi.nlm.nih.gov/pubmed/30696869
http://dx.doi.org/10.1038/s41598-018-37215-0

Ejemplares similares