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Acute glucose fluctuation impacts microglial activity, leading to inflammatory activation or self-degradation
Diabetes mellitus is associated with an increased risk of Alzheimer’s dementia and cognitive decline. The cause of neurodegeneration in chronic diabetic patients remains unclear. Changes in brain microglial activity due to glycemic fluctuations may be an etiological factor. Here, we examined the imp...
Autores principales: | Hsieh, Cheng-Fang, Liu, Ching-Kuan, Lee, Ching-Tien, Yu, Liang-En, Wang, Jiz-Yuh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351546/ https://www.ncbi.nlm.nih.gov/pubmed/30696869 http://dx.doi.org/10.1038/s41598-018-37215-0 |
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