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In silico comparison of protein-bound uremic toxin removal by hemodialysis, hemodiafiltration, membrane adsorption, and binding competition

Protein-bound uremic toxins (PBUTs) are poorly removed during hemodialysis (HD) due to their low free (dialyzable) plasma concentration. We compared PBUT removal between HD, hemodiafiltration (HDF), membrane adsorption, and PBUT displacement in HD. The latter involves infusing a binding competitor p...

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Detalles Bibliográficos
Autores principales: Maheshwari, Vaibhav, Thijssen, Stephan, Tao, Xia, Fuertinger, Doris H., Kappel, Franz, Kotanko, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351554/
https://www.ncbi.nlm.nih.gov/pubmed/30696874
http://dx.doi.org/10.1038/s41598-018-37195-1