DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions

A consistent gene set undergoes age-associated expression changes in the human cerebral cortex, and our Age-by-Disease Model posits that these changes contribute to psychiatric diseases by “pushing” the expression of disease-associated genes in disease-promoting directions. DNA methylation (DNAm) is...

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Detalles Bibliográficos
Autores principales: McKinney, Brandon C., Lin, Chien-Wei, Rahman, Tanbin, Oh, Hyunjung, Lewis, David A., Tseng, George, Sibille, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351569/
https://www.ncbi.nlm.nih.gov/pubmed/30696804
http://dx.doi.org/10.1038/s41398-019-0372-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351569/
https://www.ncbi.nlm.nih.gov/pubmed/30696804
http://dx.doi.org/10.1038/s41398-019-0372-2

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